Bromonordiazepam Powder

Brief Intro

Bromonordiazepam Powder is the active metabolite of the benzodiazepine drug Gidazepam, structurally related to Diazepam. Known for its exceptionally long half-life, Bromonordiazepam exhibits potent anxiolytic and sedative effects with limited non-therapeutic potential. It acts by enhancing GABAergic neurotransmission in the brain, producing calming and muscle-relaxant properties. This compound is used in research and forensic applications as an analytical reference standard and is not intended for human consumption.

Chemical Structure / Physical Properties

• Chemical Name: 7-bromo-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one

• Molecular Formula: C15H11BrN2O

• Molecular Weight: 315.16 g/mol

• CAS Number: 2894-61-3

• Appearance: Solid powder

• Melting Point: 220–221 °C (in ethyl ether)

• Boiling Point: Approximately 465 °C (predicted)

• Density: ~1.51 g/cm³ (predicted)

• Solubility: 5 mg/mL in DMF and DMSO; slightly soluble in ethanol; 0.12 mg/mL in PBS (pH 7.2)

• pKa: Approximately 11.7 (predicted)

Pharmacology and Mechanism of Action

Bromonordiazepam acts as a positive allosteric modulator of the GABA_A receptor, enhancing the inhibitory effects of GABA neurotransmission. This results in anxiolytic, sedative, muscle-relaxant, and anticonvulsant effects. It has a long duration of action, with effects lasting 6 to 12 hours depending on dose and metabolism. It is also reported to inhibit HIV-1 reverse transcription in vitro.

Intended Use

Bromonordiazepam Powder is intended strictly for laboratory research, forensic analysis, and pharmacological studies related to benzodiazepine metabolism and receptor interactions. It is not for human consumption or clinical use.

Packaging & Shipping

The powder is securely packaged and shipped discreetly with tracking. Typical delivery times range from 24 to 72 hours within the USA and up to 5 days internationally, depending on destination. Shipping fees are calculated at checkout based on location.

Legal & Compliance Disclaimer

All products are sold for research purposes only and are not intended for human consumption. Customers must verify the legal status of Bromonordiazepam in their jurisdiction before ordering. The vendor reserves the right to accept or decline orders based on intended use.