5-MMPA (Mephedrene) Powder

Brief Intro

5-MMPA (Mephedrene) Powder is a synthetic stimulant research chemical, formally known as 5-methylmethiopropamine. It is a ring-substituted derivative of methiopropamine (MPA) and structurally related to substituted amphetamines, lacking the β-ketone group found in cathinones like mephedrone. 5-MMPA emerged as a designer drug around 2020 and is primarily used in scientific and forensic research to study its pharmacology, metabolism, and toxicological profile. This product is strictly intended for research purposes and is not for human consumption.

Chemical Structure / Physical Properties

• Chemical Name: 5-Methylmethiopropamine (N,α,5-trimethyl-2-thiopheneethanamine)

• Synonyms: Mephedrene, 5-MMPA

• Molecular Formula: C9H15NS (freebase); C9H15NS·HCl (hydrochloride salt)

• Molecular Weight: 169.29 g/mol (freebase); 205.7 g/mol (hydrochloride)

• CAS Number: 2743746-59-8 (hydrochloride)

• Appearance: White to off-white crystalline powder

• Solubility: DMF: 10 mg/mL; DMSO: 20 mg/mL; Ethanol: 20 mg/mL; PBS (pH 7.2): 1 mg/mL

• Storage: Store at -20°C, protected from light and moisture

Pharmacology and Mechanism of Action

5-MMPA acts as a central nervous system stimulant and is structurally related to methiopropamine, a norepinephrine–dopamine reuptake inhibitor (NDRI). While specific pharmacological data for 5-MMPA are limited, it is expected to share similar stimulant properties, increasing synaptic levels of norepinephrine and dopamine. Metabolism involves hydroxylation, oxidation, N-dealkylation, and glucuronidation, with oxo-hydroxy and N-demethylated metabolites identified as biomarkers. There has been at least one reported case of acute toxicity associated with 5-MMPA.

Intended Use

5-MMPA (Mephedrene) Powder is intended strictly for laboratory research, forensic analysis, and toxicological studies related to novel psychoactive substances and stimulant pharmacology. It is not for human or veterinary consumption.

Packaging & Shipping

The powder is securely packaged and shipped discreetly with tracking. Typical delivery times range from 24 to 72 hours within the USA and up to 5 days internationally, depending on destination. Shipping fees are calculated at checkout based on location.

Legal & Compliance Disclaimer

All products are sold for research purposes only and are not intended for human consumption. Customers must verify the legal status of 5-MMPA (Mephedrene) in their jurisdiction before ordering. The vendor reserves the right to accept or decline orders based on intended use.